#ParkinsonsDisease

Recent findings underscore the critical role of exercise in slowing the progression and managing the symptoms of Parkinson’s disease, according to a 2024 analysis in the Journal of Neurology, Neurosurgery and Psychiatry. Contrary to earlier beliefs that medication alone is central to the management of Parkinson’s, a growing body of research highlights how regular, vigorous physical activity may significantly reduce both the severity and speed of symptom progression. For Thai readers—with the nation’s ageing society and increased diagnosis of chronic conditions—these findings offer actionable hope and clear guidelines for living with and managing the disease.

Thai patients and their families living with Parkinson’s disease received hopeful news this week after the US Food and Drug Administration (FDA) approved a first-of-its-kind stem cell therapy, XS-411, for Phase 1 clinical trials in the United States. Developed by biotech firm Xellsmart, this innovative therapy harnesses induced pluripotent stem cells (iPSCs) to regenerate the healthy, dopamine-producing neurons lost in patients with Parkinson’s. This marks a milestone in neurodegenerative disease treatment and offers a look toward the future of regenerative medicine, not only in the US but potentially in Thailand as global clinical research expands (Parkinson’s News Today).

Exciting news in the fight against Parkinson’s disease: Two newly published clinical studies are providing the strongest evidence yet that stem cell transplants may offer a powerful new treatment for people living with this debilitating condition. In results published this week in the journal Nature, both research teams found that surgically implanting lab-grown dopamine-producing cells into the brains of patients led to symptom improvements and no serious side effects—marking an important milestone after decades of painstaking efforts to replace the dying neurons at the root of Parkinson’s. For over a million Americans and countless others worldwide, including an estimated 150,000 Thais suffering from Parkinson’s, this research signals fresh hope for dramatically improving quality of life in the coming years (NPR).

Deep within the forests and fields of Thailand, the twisting vines of หมามุ่ย (Mucuna pruriens), known colloquially as “Mahamui,” have been harvested for generations, their itchy seed pods treated with caution but their hidden treasures—the seeds—prized by traditional healers. For centuries, Thai folk medicine has celebrated this legume for supporting male vitality, easing nervous ailments, and, notably, restoring sexual health. Today, as modern researchers crack open the mysteries inside its tiny beans, Mucuna pruriens stands at the intersection of ancestral wisdom and cutting-edge science, offering a compelling case for the harmonious coexistence of traditional and evidence-based medicine.