#PfizerVaccine

A Turkish study reports a potential, short-term change in the cornea following Pfizer-BioNTech vaccination. Researchers observed small increases in corneal thickness and a decline in endothelial cell density after vaccination, but the changes were temporary and did not visibly affect vision in study participants.

The study tracked 64 adults who received the Pfizer vaccine, with imaging before the first dose and about two months after the second dose. The corneal endothelium kept the eye clear and showed an average thickness rise from 528 to 542 micrometers, about 2 percent, while endothelial cell density fell from roughly 2,597 to 2,378 cells per square millimeter, an 8 percent drop. Cells also showed more size variation and fewer hexagonal shapes, indicating cellular stress.

A newly published medical study has identified a potential connection between the Pfizer-BioNTech COVID-19 vaccine and changes in the cornea—the transparent front part of the eye—raising questions about possible implications for certain individuals at risk of vision problems. While researchers have emphasized that the detected changes appear to be temporary and have not led to loss of vision in the study group, these findings raise important considerations, especially for people with pre-existing ocular conditions.