#Phytochemistry

Few herbal medicines echo across as many generations and regions as chùm hèt thét (ชุมเห็ดเทศ), known to scientists as Cassia alata L. or Senna alata. Recognized in Thai as ขุมเห็ดเทศ, and by names such as chùm hèt yài, lúp mạn lûang, chî khàak, màak kà-líng thét, and sôm hèt, this striking “candle bush” is both common roadside greenery and a staple of traditional household pharmacies. Its yellow, candle-like flowers catch the eye, but it is the fresh and dried leaves—harvested in villages throughout the Kingdom—that have solidified its central role in herbal practice. Today, chùm hèt thét’s journey from ancient remedy for skin diseases and constipation to evidence-based pharmaceutical candidate reveals a fascinating intersection of culture, folk wisdom, and modern science—one vital to Thai readers seeking a bridge between old and new approaches to health.

Jetaphangki, known scientifically as Cladogynos orientalis, grows along forest trails in Thailand and neighboring regions. Locally it is called Jetaphangki, Chettaphangki, plao ngam, and tawng ta phran, reflecting deep cultural roots. For generations, its roots and leaves have been used in Thai traditional medicine to ease stomach issues, boost vitality, and support general wellness. Today, scientists are reexamining these claims with modern methods, while Thai communities remain curious about harmonizing heritage with evidence.

For generations, the vine known across Thailand as โคคลาน or “Koh Khlan” has been a wellspring of traditional healing. Behind this name are other local monikers—มะกายเครือ, มะปอบเครือ, กระเปี้ยะ, โพคาน, แนวน้ำ, เยี่ยวแมว, เยี่ยวแมวเถา—reflecting its widespread recognition in rural and forested communities from the northern hills to the heart of Isan. Scientifically catalogued as Mallotus repandus (Willd.) Müll. Arg., this robust member of the Euphorbiaceae family is best known in Thai traditional medicine for alleviating muscle, bone, and joint pains, often earning its place in time-honoured herbal mixtures for ailments that sap vitality and disrupt daily life.

Koh Khlan, known across Thailand by several local names such as makay kreua and yeo maeo, has long been a source of traditional healing. In rural communities from the northern hills to Isan, families rely on its bark, leaves, and stems to ease muscle, bone, and joint pains. Scientifically, the plant is Mallotus repandus, a member of the Euphorbiaceae family, widely used in Thai herbal blends that aim to restore vitality in daily life.

Chandan khao, also known as white sandalwood, has long been a traditional remedy across Thailand, Cambodia, and Vietnam. The tree behind this name is Tarenna hoaensis Pit., sitting at the crossroads of heritage and scientific curiosity. Ancient practitioners praised its aromatic heartwood for cooling effects and fever relief, while today researchers explore its biochemical properties for potential medical use.

To understand chandan khao’s place in Thai culture, it helps to note how aromatic woods feature in local traditions. Although related to Indian sandalwood, chandan khao’s medical role remains distinctly Southeast Asian. Healers have used mature heartwood to fashion cooling balms, anti-fever preparations, and soothing infusions. These practices fit a hot, humid climate where cooling remedies are especially valued.

Nestled in the lush landscapes of Thailand, Cambodia, and Vietnam, a distinctive hardwood known locally as “จันทน์ขาว” (chandan khao, or white sandalwood) has quietly served generations as a cornerstone of traditional healing. The botanical hero of this story, Tarenna hoaensis Pit., holds a place not only in herbal lore but also on the threshold of contemporary scientific curiosity. While ancient practitioners revered its aromatic wood and heartwood extracts as cooling agents, fever reducers, and components of ceremonial offerings, today’s researchers are beginning to unlock its deeper biochemical secrets, exploring the very real possibility that chandan khao holds pharmacological promise fit for modern times.

Across the winding hills and sacred forests of Thailand, few plants carry a legacy as rich as จันทน์แดง (Chandan Daeng), known botanically as Dracaena loureiroi. The deep red core of its wood, prized for generations, has not only painted the color palette of Buddhist altars and traditional handicrafts, but also infused traditional Thai medicine (TTM) with a symbol of vitality, healing, and spiritual protection. As global interest in herbal medicine surges, Chandan Daeng stands at the powerful intersection of cultural reverence and science-backed discovery, inviting both renewed appreciation and critical questions about its role in modern wellness.

Deep in the heart of Southeast Asia, along the forested trails of Thailand and neighboring countries, grows a humble shrub known by many names—Jetaphangki, Chettaphangki, and a host of local monikers such as “plao ngam” and “tawng ta phran.” For centuries, the roots and leaves of Cladogynos orientalis, or Jetaphangki, have been prized in traditional Thai medicine cabinets, used to soothe stomach troubles, restore harmony, and invigorate the body. Today, scientists and health seekers alike are rediscovering this botanical treasure, probing its traditional roots while putting its ancient claims to the test.

For generations, the robust trees of Knema angustifolia—known in Thai as กำลังเลือดม้า (gamlang lueat ma) or sometimes as ประดงเลือด, and in English by its scientific name—have quietly offered their bark to folk healers across Thailand’s countryside. Local herbalists, passed down wisdom through word of mouth, have prized its blood-red sap for its reputed power to invigorate blood, fortify the body in times of weakness, and ease various ailments. Today, as the world looks anew at traditional remedies, a new chapter is being written for this storied botanical, reaching from Lanna village clinics to the cutting-edge labs of modern phytochemistry and pharmacology.

For centuries, the mysterious Kamlang Suea Khrong—literally, “Tiger’s Strength”—has been renowned throughout Thailand as a traditional elixir promising stamina, vitality, and resilience. Borrowing its name from brute force and feline grace, this herbal medicine is shrouded in local wisdom, handed down through generations as both a standalone remedy and a prized ingredient in restorative tonics. But as modern science peels back the layers of legend and lore, new questions arise: How much of the “tiger’s power” is rooted in pharmacology, and what do contemporary studies reveal about its efficacy and safety?

Across Thai villages and markets, Kan Tee Saw (Vitex trifolia) has long been valued as a versatile healer. In regions from Chonburi to the North, this unassuming shrub is known by many local names, reflecting Thailand’s cultural diversity and deep plant knowledge. Today, researchers are investigating Kan Tee Saw with modern methods, turning ancient remedies into potential scientific insights while preserving its cultural significance for Thai communities.

Vitex trifolia is modest in size but historically powerful in Thai ethnomedicine. The plant’s seeds are prized for their cooling, cleansing, and gentle stimulating qualities. Traditional practitioners use Kan Tee Saw to address a range of ailments—from fevers and headaches to respiratory issues and skin conditions—often integrating it into broader herbal recipes for digestive upset, wounds, and postpartum care. This broad utility has cemented Kan Tee Saw as a mainstay in folk health practices across the country, with practitioners citing generations of experience and regional formularies.

Nestled in the folklore and village gardens across Thailand, the unassuming Kan Tee Saw—known scientifically as Vitex trifolia—has for centuries been revered as a multifaceted healer. Called by names as varied as kan tee saw khaw in Chonburi, khon din saw in the central regions, phii suea noi in the North, or thian khaw in Phetchaburi, this plant’s rich medicinal history threads through every region and dialect, embodying a unique harmony of nature’s bounty and human ingenuity. Today, as researchers turn magnifying lenses and test tubes onto the ancient remedies of Thai traditional medicine, Kan Tee Saw emerges not just as a cultural artifact but as a botanical protagonist on the cusp of scientific validation. What follows is a journey through its uses, lore, modern research, and what the future may hold for this cherished herbal medicine.

Streblus asper, known locally as Khoi, has long been a steadfast companion in Thai homes and communities. Revered in traditional healing, embedded in folklore, and tied to early Siamese literacy, the tree is more than a plant — it is a cultural symbol. Today, researchers are reexamining Khoi to understand its real potential in modern health while honoring its heritage.

In Isan and other rural regions, Khoi twigs were once chewed as a daily dental care practice. Murals in Ayutthaya even depict children using Khoi bark, illustrating its enduring place in daily life and ritual. The wood’s bitter aroma and distinctive texture have made it a go-to for personal care for generations. But what does current science say about Khoi’s safety and effectiveness?

In the world of Thai traditional medicine, few remedies conjure as much intrigue as “khon dok” (ขอนดอก), a unique crude drug derived not from the foliage or flowers of a plant, but from the fungus-infused heartwood of ancient trees, specifically the sacred “pikul” (Mimusops elengi) and “tabak” (Lagerstroemia calyculata). Revered for centuries across the region, khon dok resonates as an intersection of deep-rooted animist tradition, classical Thai and Ayurvedic healing, and emerging biomedical research. Today, as both practitioners and scientists re-examine humble old formulas in the quest for greener, more localized therapeutics, the story of khon dok stands as a compelling model of how ancient wisdom and modern science can harmonize.

Khon dok is a remarkable Thai traditional remedy drawn from fungus-infused heartwood, not leaves or flowers. It comes from pikul or tabak trees and is used in many communities to support digestion, heart health, and as a general tonic. Today, researchers are re-examining this ancient formula as interest in local, sustainable medicines grows.

Thai herbalists across the central, northern, and northeastern regions have long valued khon dok for its purported astringent, cooling, and anti-inflammatory properties. In the era of antibiotic resistance and concerns about side effects from synthetic drugs, scientists are revisiting khon dok to understand what makes the wood-fungus complex potentially beneficial.

For generations, Thai communities have trusted the bark of Knema angustifolia, known locally as กำลังเลือดม้า (gamlang lueat ma) and sometimes as ประดงเลือด, as a traditional tonic. Folk healers described its red sap as a source of vitality, used to strengthen the body during weakness and to support recovery from illness. Today, researchers are revisiting this tree to understand its potential through contemporary phytochemistry and pharmacology, connecting village practices with modern science.

Kamlang Suea Khrong, literally translating to “Tiger’s Strength,” has long stood as a cornerstone of Thai traditional medicine. The herb is believed to boost stamina, vitality, and resilience, and its name evokes both raw power and wild vitality. Today, researchers and health-conscious Thai readers are exploring what modern science says about its efficacy and safety, while preserving its cultural significance.

Known in botanical terms as Strychnos axillaris Colebr., Kamlang Suea Khrong has historically been used as a decoction or as a component in restorative tonics and ya dong, the herbal-infused spirits popular in traditional culture. Healers describe its role in revitalizing energy, soothing muscle discomfort, and supporting overall balance within the body—a view rooted in Thai holistic wellness. The herb’s enduring appeal lies in its ability to bridge ancestral knowledge with contemporary curiosity, attracting interest from those seeking natural alternatives and prompting scientific inquiry.

Thai traditional medicine has long valued the dried rhizome of Neopicrorhiza scrophulariiflora, known locally as โกฐก้านพร้าว. This rare alpine herb sits at the crossroads of ancient rituals, folk healing, and contemporary research. Thai herbalists also call it กะฎุกะ or กฏุโรหินี, and its roots feature prominently in traditional cabinets, Buddhist ceremonies, and growing scientific interest. Across Southeast Asia and the Himalayas, researchers are asking what makes this plant a staple for fevers, digestive concerns, and protective healing. Today’s overview ties its cultural significance to current science, with Thai readers in mind.

Hidden in Thailand’s forests, a climbing shrub known as Salacia chinensis, or กำแพงเจ็ดชั้น, has a storied role in traditional Southeast Asian medicine. Locally it goes by names such as ตะลุ่มนก, ตาไก้, ขอบกระด้ง, and หลุมนก. Researchers are now exploring its traditional uses through the lens of modern science, uncovering insights that both support and refine age-old practices.

Traditionally, communities in Thailand have used the plant’s woody stems and roots to support heart health, improve circulation, reduce inflammation, and manage blood sugar. In many rural households, a bitter decoction made by boiling the plant is consumed alone or blended with other herbs. Elders recall how a “hot constitution” or fatigue could be addressed with the plant’s tonic properties. In Thai folk practice, กำแพงเจ็ดชั้น is valued as a rejuvenator and is used differently across regions, reflecting a deep, regionally diverse healing culture.

For centuries, the sturdy branches of ข่อย (Khoi)—scientifically known as Streblus asper—have woven through the everyday lives and healing traditions of Thailand and its Asian neighbors. Revered in traditional medicine, immortalized in local folklore, and even etched into the chronicles of early Siamese literacy, this unassuming “toothbrush tree” continues to captivate the attention of healers and scientists alike. Today, the resurgence of interest in natural health remedies repositions Khoi not just as an artifact of folk heritage, but as a candidate for contemporary herbal medicine, demanding a closer look at the science behind its storied reputation.

When it comes to traditional Thai medicine, few remedies evoke as much curiosity and reverence as โกฐก้านพร้าว (Neopicrorhiza scrophulariiflora), a rare alpine herb whose story weaves through the misty foothills of the eastern Himalayas and the centuries-old apothecaries of Southeast Asia. Known to Thai herbalists as both โกฐก้านพร้าว and by a host of evocative regional names—including กะฎุกะ and กฏุโรหินี—this plant’s dried rhizome remains a prized ingredient in classic medicine cabinets, Buddhist rituals, and even modern-day scientific investigations (phar.ubu.ac.th; Disthai.com).

Among Thailand’s lush forests, hidden beneath the embrace of tangled vines and sturdy trunks, grows a climbing shrub with a storied past and promising future: กำแพงเจ็ดชั้น, or Salacia chinensis. Known by myriad regional names such as ตะลุ่มนก, ตาไก้, ขอบกระด้ง, and หลุมนก, this plant has been treasured in traditional Thai and Southeast Asian medicine for centuries. Today, as researchers peel back the layers of its traditional use, they’re uncovering scientific evidence that validates (and in some cases, challenges) the age-old practices of herbalists and healers.

Beneath the dappled canopies of Thailand’s evergreen and deciduous forests, a modest woody climber has quietly served as an ally in the country’s traditional medicine for generations. Known as “กำแพงเก้าชั้น” (Kamphaeng Kao Chan), or by local names such as “ตากวง” and “ตากวาง” in Northeastern dialects, Salacia verrucosa Wight. represents a remarkable bridge between ancient healing traditions and modern scientific investigation. As renewed interest in natural remedies sweeps across global wellness communities, this indigenous herbal medicine invites a closer look—not only for its practical benefits but for the cultural wisdom encoded in its bark and roots.

A modest woody climber thrives in Thailand’s forests, quietly bridging ancient healing and modern science. Kamphaeng Kao Chan, known locally as ตากวง and ตากวาง in Northeastern dialects, belongs to Salacia verrucosa. Its bark and roots have long been part of Thai traditional medicine, offering a glimpse into how culture and chemistry intertwine in everyday health practices. As global interest in natural remedies grows, this plant invites a closer look for its practical value and the cultural wisdom it embodies.