#Pulmonaryhypertension

In a focused study led by researchers in Japan and published online in late 2025, a striking 44% of people with systemic sclerosis (SSc) who report exercise intolerance showed exercise-induced pulmonary hypertension (PH). Even more notable, about 30% of the same group had PH at rest. The study also found that nailfold capillary density—an accessible skin-based measure—was notably lower among those with PH and exercise-induced PH, offering a potential early clue for clinicians. The researchers emphasize that a small set of clinical features during exertion, together with a simple nailfold capillary assessment, might help identify patients at risk who would benefit from more definitive testing, such as exercise right heart catheterization.