#Spermidine

A recent study published in the Journal of Affective Disorders reveals that older adults who consume greater amounts of spermidine—a compound found in foods like aged cheese, mushrooms, and whole grains—tend to perform better on cognitive function tests. This finding offers a promising dietary strategy for Thailand’s rapidly aging society, where cognitive decline and dementia are growing health concerns.

The research team, led by a scientist affiliated with a U.S. university, analyzed data from over 2,600 Americans aged 60 and above, using the U.S. National Health and Nutrition Examination Survey (NHANES) conducted by the Centers for Disease Control and Prevention. Participants reported their diets through two 24-hour dietary recall interviews and completed four standardized cognitive assessments. The results showed a clear trend: those in the highest quarter for spermidine intake consistently achieved better cognitive test scores than peers with lower intake. Notably, the beneficial link was most pronounced in males, non-Hispanic whites, individuals classified as somewhat overweight (BMI 25–30), and those with hypertension or high cholesterol (PsyPost).

A growing body of scientific research is positioning spermidine—a naturally occurring compound found in certain foods and within the human body—as a potential “Swiss army knife of longevity,” offering wide-ranging benefits from heart and brain health to hair growth and immune support. The latest synthesis of this trend, highlighted in a recent piece from the New York Post, explores emerging evidence on spermidine’s ability to slow aging, support hormone balance, and promote healthier hair and internal organs, drawing intense interest among scientists, clinicians, and health-conscious citizens globally—including in Thailand.

A naturally occurring compound, spermidine, is emerging as a powerful ally in the quest for a longer and healthier life, with recent research and expert opinions highlighting its potential benefits for the brain, heart, immune system, and even hair growth. Described as the “Swiss army knife of longevity” by leading figures in wellness research, spermidine’s allure comes from both scientific evidence and its availability in a range of foods that are familiar to Thai households.