#SubstanceAbuse

A groundbreaking study from Aarhus University has revealed that long-term addiction to substances like cocaine and heroin fundamentally shifts how people experience pleasure from music, offering new insights that may transform addiction treatment and rehabilitation practices worldwide, including in Thailand. The research found that individuals with substance use disorders require far more complex rhythms and harmonies in music to experience the same pleasurable urge to move—referred to as “groove”—that most people feel with much simpler beats. This discovery, published in the Proceedings of the National Academy of Sciences and recently highlighted in a summary at MedicalXpress, uncovers how deeply drug dependency changes the brain’s reward system beyond drug-related cues.

A wave of fresh research is prompting Thai psychiatrists and families to reconsider long-held assumptions about psychosis, as scientists explore the crucial differences between substance-induced and primary psychotic disorders. This emerging body of evidence, highlighted in a recent Medscape report, could help guide better diagnosis, tailored treatment, and more hopeful outcomes for patients across Thailand.

Psychosis, a condition marked by a loss of contact with reality—often via hallucinations or delusions—has long been categorized into those primarily caused by a psychiatric illness, like schizophrenia, and others triggered by substance use, such as methamphetamine (“ya ba”) or cannabis. Understanding whether symptoms are “primary” (intrinsic to psychiatric illness) or “substance-induced” (caused by drug or alcohol use) shapes every aspect of medical care, but until now, the true distinctions have often been blurred, fueling debates among clinicians and researchers worldwide.