#Sucralose

Recent research has uncovered potential risks associated with the ubiquitous artificial sweetener sucralose, marketed widely as Splenda. Conducted by experts at the University of Southern California, the study presents intriguing insights into how sucralose might intensify hunger by influencing brain activity, particularly in the hypothalamus—a crucial area for regulating appetite. A randomized crossover trial involving 75 adults demonstrated that consuming sucralose led to a distinctive pattern of heightened blood flow in the hypothalamus, in contrast to sucrose (table sugar), which showed a hunger-reducing effect.

A recent study by researchers at a leading U.S. university suggests that sucralose, a common artificial sweetener, may increase hunger by altering brain signals in the hypothalamus, the region that controls appetite. In a randomized crossover trial with 75 adults, participants who drank sucralose showed higher hypothalamic blood flow than those who consumed sugar, which tended to reduce hunger. The results point to a potential mismatch between sweetness and calories, influencing how the brain responds to sweet taste.