#Visualsystems

An international team of more than 150 scientists has created the most detailed map to date of how visual information travels through the brain. The study uncovers hundreds of millions of connections within a single grain-sized sample of mouse brain tissue and brings researchers closer to understanding sight. Published in Nature on April 9, 2025, the project combines genetic engineering, high-resolution electron microscopy, and deep learning to chart both the physical wiring and the neurons’ real-time responses to visual stimuli. The result is a 1.6-petabyte dataset—a scale comparable to 22 years of continuous high-definition video—capturing a microscopic brain fragment in extraordinary detail.

A groundbreaking international study led by over 150 scientists has produced the most detailed map ever of how visual information moves through the brain, uncovering more than 500 million intricate connections within a speck of mouse brain tissue and bringing the world closer to understanding how we see. Published in the journal Nature on April 9, 2025, the research combines genetic engineering, high-powered electron microscopy, and deep learning to capture not only the physical wiring of over 200,000 brain cells but also their real-time electrical activity in response to visual stimuli. The project—hailed as one of the most complex neuroscience experiments ever attempted—has generated a dataset of unprecedented size and detail: 1.6 petabytes, about the equivalent of 22 years of continuous high-definition video, all representing a single grain-sized fragment of brain.