#YouthPrevention

A new synthesis of 25 years of global research links certain hormonal patterns to psychopathic traits, offering fresh angles for early intervention among at-risk youths. The analysis suggests biology and behavior are more intertwined than once thought. In Thailand, where youth behavior and mental health are policy priorities, these findings could inform holistic prevention strategies that combine education, health services, and social support.

Across 26 studies, researchers examined hormones such as cortisol, testosterone, estradiol, oxytocin, and DHEA in adolescents and young adults. The most consistent finding is that higher resting cortisol levels—the body’s main stress hormone—are associated with impulsive and antisocial aspects of psychopathy, rather than emotional detachment alone. This nuance challenges older ideas and points to a dynamic link between biology and conduct.

A new meta-analysis has shed light on the complex links between hormonal activity and psychopathic tendencies, raising the prospect of more nuanced approaches to identifying and supporting at-risk youth. The study, published in Psychology & Neuroscience, draws on 25 years of worldwide research and upends some previous assumptions about the biology of personality disorders, with potential implications for prevention and mental health services in Thailand and beyond (psypost.org).

At its core, the research reviewed studies examining the role of endocrine system hormones—such as cortisol, testosterone, estradiol, oxytocin, and dehydroepiandrosterone (DHEA)—in the development of psychopathic traits, especially during the sensitive years of adolescence and early adulthood. The strongest and most consistent finding was a statistically significant association between higher baseline levels of cortisol—the body’s primary stress hormone—and the impulsive, antisocial dimension of psychopathy.